Hey guys here you are some of my notes about nucleophilic substitution, just follow the dropbox link and you will have access.
What I speak about in this notes?
- SN1 and SN2 mechanism and kinetic of both
- Stereochemistry
- How structural variations can affect substitution
- Steric hindrance
- Solvent effect
- The leaving group
- Mitsunobu reaction
- Ethers
- Epoxides
- Nitrogen nucleophiles
- Azide
- Sulphur
- Effectiveness of different nucleophiles in the SN2 reaction
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